[There’s no evidence for this (yet?), but I have ZERO doubt that the makers of O, M, and all the others are preparing a vigorous smear campaign for studies like these.]
I’m writing to say that my own experience of reducing my Ozempic injections to once every other Sunday (my day for injections) supports the study linked below.
From the study, “In a small new study, most people who switched from weekly to every-other-week GLP-1 dosing maintained their weight loss and metabolic health improvements. [A fraction of the people regained weight and needed to return to weekly injections — suggesting close monitoring is important when reducing dose frequency.] While I have NOT regained weight and have NOT returned to a weekly dose. People who want to reduce their dose or space out GLP-1 injections should always consult their provider first.”
I talked with my doctor before getting off Ozempic on January 24, 2026, he supported my move, and with his concurrence, I stopped taking it every week.
I could share the actual data with you, but what you would see is NOT a miraculous return to the response of a person who is NOT insulin resistant – but you WOULD see someone who works to exercise regularly, watches both WHAT he eats and HOW MUCH he eats.
What you will NOT see is a man who has become acetic – only eating salads, twigs, single bites of fat-free yogurt (I have a cup of fat-free or low-fat yogurt a week and a cup of either fat-free or low-fat cottage cheese a week. These dairy products are mixed with (mostly) whatever fresh fruit is available at the grocery store (like raspberries, blackberries, apples, pears, and strawberries) mixed with a cup of either cottage cheese OR yogurt, and sweetened with Splenda – NOT to “ward off the effects of Ozempic”, but because I need to eat that amount of calcium twice a week so I don’t get cramps in my calves!
I confess that I DO have the occasional Dairy Queen PB Parfait or some scoops of ice cream during the week. I also walk a straight mile (ie – I have a route that I’ve clocked and know exactly how long and how far I go when I walk from our house to a nearby cemetery.); then add in whatever else my cell phone’s step counter has recorded. I’ll confess also that I am NOT religious about how much I walk…
My OTHER faith, “Minnesota Winter Weather Variation” has grounded me more than once. OTOH, I walked once day when the air temperature was -7F and the windchill gave the air a “feels like/ability to freeze skin” temperature of -36F (of course, that’s more to prove that I am still, indeed a Minnesotan)! I also now park as far out as I can in the grocery store or Target or church parking lot and walk into the building – no matter the temperature.
So…I did in fact reduce my use of Ozempic from weekly to bi-weekly. My starting physiological data are as follows:
2/24/2023 BP:155/180 Weight: 253.8 Blood Glucose: 189
9/7/2025 STARTED OZEMPIC BP:122/75 Weight: 241.2 Blood Glucose: 171
2/25/2026 BP: 120/75 Weight: 230.6 Blood Glucose: 145
Data indicates that when I DON’T walk, my BP and Glucose are higher. Weight can’t be measured as a “daily thing”, rather as a range. For example when I was originally diagnosed with Type2, I weighed 260.8 in April of 2023. Exercise and watching what I ate DID have an effect on my health. Ozempic initially help me break a barrier.
Because I’ve lately been drifting into the high 220’s with my Winter regimen, I’m going to work to push it lower when I take to my bike this Summer. We originally bought our house because it was adjacent to a park that is connected to biking/walking trails stretching from northern Minnesota, west to the Great Plains (North and South Dakota), south to Rochester and some go East into Wisconsin. I can literally ride the entire state and slices of three others and with the right permits, north into Canada!
I LOVE biking, and it’s stayed with me since I was a teenager and was biking to get away from my “sports-obsessed-family” – of course three activities I loved (biking, swimming, and camping) weren’t “sports-enough” for them…and, “Yes, you DO sense a bit of bitterness in my tone!” At any rate, I’m looking forward to losing a few more pounds (my recent A1c dropped to 6.2 about a month ago!), and seeing my daily blood sugars more often in the 140s rather than the 150s.
I’ll keep you posted! Have a great week!
Source: https://www.everydayhealth.com/weight-management/can-taking-glp-1-drug-every-other-week-help-you-keep-weight-off/ ; https://pmc.ncbi.nlm.nih.gov/articles/PMC11885104/ Image: https://aeroflowdiabetes.com/media/wysiwyg/diabetes-guide-booklet-aeroflow-diabetes.jpg
