Sunday, February 25, 2024

DIABETES RESEARCH RIGHT NOW! #14: Metformin + MORE Meds? – Almost Half of Us REFUSE...Why?

From the first moment I discovered I had been diagnosed with DIABETES, I joined a HUGE “club” that has been rapidly expanding since it stopped being a death sentence in the early 20th Century. Currently, there are about HALF A BILLION PEOPLE who have Type 2 Diabetes. For the past 3500 years – dating back to Ancient Egypt – people have suffered from diabetes. Well, I’m one of them now… Not one to shut up for any known reason, I added a section to this blog…

Every month, I’ll be highlighting Diabetes research that is going on RIGHT NOW! Harvested from different websites, journals and podcasts, I’ll translate them into understandable English and share them with you. Today: People Refuse to Take More Metformin, or Refuse to Follow the Prescription…HUH???


Sometimes someone with Type 2 Diabetes can’t get their blood sugars under control with exercise, diet, and the maximum 4-Metformin-pills-a-day prescription. Barring the person who refuses to exercise and change their ANYTHING that they do (a former friend of mine passed away recently because they flat out refused to take care of themselves); doctors sometimes have to add a “second-line” drug to help manage blood sugars. Prescribing insulin; Saxenda or Victoza; Januvia or TreviaMet; or Jardiance is usual depending on the individual’s diabetes peculiarities.

A new Northwestern Medicine study, however, has shown that USING the prescribed what are called second-line drugs that may be important in managing blood sugars, “can be hit or miss”.

Let’s review why it’s important for someone (like ME!) who’s been diagnosed with Type 2 diabetes, to control my blood sugar (or glucose levels).

I’m gonna lift this directly from “Keeping your blood sugar at or near your goal level helps decrease the risk of complications that can affect the eyes, kidneys, and nerves. Keeping your blood pressure and cholesterol levels under control helps reduce your risk of heart disease, which is a common complication of type 2 diabetes. Many factors affect how well a person's diabetes is controlled. You can reduce your risk of complications by following your health care provider's guidance around diet, exercise, blood sugar monitoring, and medication regimens. Dietary changes are typically focused on eating nutritious foods and getting to (and maintaining) a healthy weight. If you take insulin, you may also need to be consistent about what you eat and when…”

But if the FIRST line of exercise, diet, and drugs DOESN’T work – you need a second if you want to continue to live a reasonably healthy life. Apparently some people either have to actually make changes or take more medications. Admittedly, “while the scientists did not have data on reasons why patients discontinued treatment…it may have been due to side effects like nausea, vomiting and diarrhea -- which have been observed in patients who take these medications for diabetes control and for weight loss…”

“The study of more than 82,000 patients between 2014 and 2017 found that after a year of their first set of meds, (FIFTY THOUSAND OF THEM) either discontinued their medication, switched to a different medication class, or intensified their treatment. Stopping your meds is bad. It is common in all five types of medications.”

WHY???? It’s not like people are “alone” in their diagnosis: “In total, half of all adults and a quarter of teenagers have diabetes or pre-diabetes.”

It’s not like we don’t KNOW what ignoring our Type 2 diabetes will do: “…heart attacks, amputations, blindness, kidney disease, double the risk of premature death, “diabetes distress”, “dips in energy, foggy thinking and depression, and a sense of isolation”, and as a matter of history, “Roughly 40% of people who died early in the pandemic had Type 2 diabetes, a rate four times higher than people without the disease.”

So, science KNOWS how to treat it – why do we prefer to IGNORE it?

There ARE, absolutely things in the world around us that drag us into a lifestyle that can lead to Type 2 diabetes – fast food, the “drive everywhere” of American lifestyles, for me it was plain old laziness. “There’s no question personal responsibility plays a role in fighting diabetes…They’ve reduced their dependence on daily medication and hope to have saved themselves the horrors of more amputations, blindness and dialysis. They’ve extended their lives and improved the quality of that time. But like many medical problems, the challenges of diabetes go well beyond individual responsibility and blame…even in Colorado, where hiking trails and gorgeous views abound – economic and other disparities make it easier for some people to avoid diabetes than others.”

Ultimately, it lies with ME to change. Read the USA Today article – it’s long, but it also ends this way: “…he clings to his faith and the positive attitude he has long used to cheer up himself and others. These are his secret weapons against diabetes and everything else life throws his way. ‘I try to put a smile on other people's faces,” he said. “It keeps my day going.’”

Links: https://www.sciencedaily.com/releases/2023/12/231212112312.htm; https://www.uptodate.com/contents/type-2-diabetes-and-diet-beyond-the-basics/print#:~:text=Keeping%20your%20blood%20sugar%20at,complication%20of%20type%202%20diabetes. ; https://www.usatoday.com/story/news/health/2023/10/01/type-2-diabetes-prevention-progress/70768126007/ Image: https://asploro.com/wp-content/uploads/2019/12/Diabetes-Research_Open-Access.jpg

Sunday, February 11, 2024

GUY’S GOTTA TALK ABOUT…TYPE 2 DIABETES #19: Exercise LOWERS Blood Sugars!!!!

For the first time since I started this blog eleven years ago, it’s going to be about me. I was diagnosed with Type 2 Diabetes two weeks ago. While people are happy to talk about their experiences with diabetes, I WASN’T comfortable with talking about diabetes. My wife is Type 2, as are several friends of ours. The “other Type” of diabetes was what caused the death of my Best Man a year after my wife and I got married. He was diagnosed with diabetes when he was a kid. It was called Juvenile Diabetes then. Today it’s Type 1. Since then, I haven’t WANTED to talk about diabetes at all. But…for my own education and maybe helping someone else, and not one to shut up for any known reason, I’m reopening my blog rather than starting a new one. I MAY take a pause and write about Breast Cancer or Alzheimer’s as medical headlines dictate; but this time I’m going to drag anyone along who wants to join my HIGHLY RELUCTANT journey toward better understanding of my life with Type 2 Diabetes. You’re Welcome to join me!


OK, FACT is that I very much DISLIKE exercise. Really HATE IT, actually! But when someone says, “I exercise!”, this is what my mind conjures:

https://image1.masterfile.com/getImage/700-02798065em-man-on-treadmill-stock-photo.jpg

It says to me, “BORING! ENDLESS! STUPID!”

One or two of you know what I mean.

The other side of me says, “But my blood sugars and blood pressure go down when I exercise!” You know, the “My doctor says that I should exercise to lower my blood sugars and blood pressures and lose some weight…” lectures.

This is what my mind conjures: 

https://media.gettyimages.com/id/74878707/photo/mature-doctor-with-stethoscope-portrait.jpg?s=612x612&w=0&k=20&c=yEvDUO9q1xD8QdX_6ZccXVKoCBidszgMc2a_leYmBr8=

One or two of you might know what I mean.

So, I set out to figure out what I can do to exercise – that isn’t the first image and WON’T trigger the second image.

From the day I got a three-speed bike for a Confirmation gift when I turned fifteen – to three or four years after we moved into our new house, I’ve been a biker.

I DON’T DO RACING! (Though I started doing biking for fund raising. My first “bike-a-thon” was for the March of Dimes when I was sixteen…(of course, I’d ditched the three-speed my parents got me and bought a REAL ten-speed!) 

I had no idea how far the ride was THEN, but I calculated it recently and found that with only regular biking (to work and home again) plus my age (16), I’d biked 49 miles with little to no effort.

That was the beginning. About six years ago, I picked up biking again. It started with my janky ten-speed bike. Then the school district I work for offered a perk: they’d give me $600 toward ANY health thing I wanted! Gym membership! Diet program! Treadmill! Home gymnasium! Personal trainer! Nice bike…

Hmmm…so, $600 in hand, I bought a $1000 bicycle from Trailhead Cycling in Champlin, MN and only paid $400. A basic Giant, it was strong, sturdy, and I even splurged and bought the Old Man Bicycle Seat so my butt wouldn’t go numb any more. I DON'T have biking shorts or a biking outfit or biking shirt or any of that other crap. I wear a helmet and shorts and tennis shoes and a T-shirt. I absolutely REFUSED to get dolled up to ride my bike and get sweaty!

And then I started biking. Initially, I rode a short loop – end of the block, around and home. *whew* It had been a LONG time since I’d made any serious effort at riding. Getting used to the new bike. (Put the old 10-speed on the curb and it was carted away for scrap (I suppose)…) I rode three miles around the nearby marsh. Did that for a few weeks, building up endurance only on weekends. Worked up to five miles, maybe ten on the weekends.

My teen-year love of biking reignited! I wasn’t doing it to “get healthy!” or “lose weight!” or even…“cause it’s good for you!” I was biking because I LIKED IT! All that other crap was beside the point. I LIKED BIKING – I wasn’t “exercising”…I was doing something I’d loved since that first 3-speed when I was fifteen.

From there, I kept going. I rode all summer, then asked my son to ride with me on the Grand Round Scenic Bikeway – it was a fifty-one mile ride around Minneapolis and St. Paul, sometimes cutting through the cities down the street in a designated Bike Lane. Other times riding along the Mississippi and pulling up behind Fort Snelling…then finishing up weaving around Minneapolis’ famous Lakes: Bde Mka Ska, Harriet, and others I don’t even remember. We signed up for a couple of fund raisers – breast cancer; MS; Diabetes…

And by then, I was hooked. But I wasn’t “exercising”. I was ENJOYING MYSELF! That was the key for me – exercising? (spit on the ground) – was a total NON-motivator for me. So, what is it that YOU LIKE TO DO? I’m sorry, it does require MOVING. But some moving is better than NO moving. So find that moving thing you like and keep doing it, setting little, teeny goals for yourself. I’ll share more next time around about what’s happened in the decade since I was riding in those fund raisers…

So MOVE! Here's a link to our own Minnesota Health giant that promotes this very thing! The Mayo Clinic -- https://www.mayoclinichealthsystem.org/topics/move-more

Image: https://www.hcd.com/wp-content/uploads/2021/01/living-well-with-diabetes.jpg