Saturday, November 30, 2013

A Fantastic Cancer Voyage Chapter 2 IV

From the first moment my wife discovered she had breast cancer, there was a deafening silence from the men I know. Even ones whose wives, mothers or girlfriends had breast cancer seemed to have received a gag order from some Central Cancer Command and did little more than mumble about the experience. Not one to shut up for any known reason, I started this blog…
 
One of my fondest memories as a kid is watching the movie FANTASTIC VOYAGE. In it, a group of scientists and their ultra-futuristic laser-packing “submarine” are reduced to cell size and injected into the blood vessels of a world diplomat in order to destroy a blood clot in his brain.
 
What would a FANTASTIC VOYAGE: Breast Cancer look like? I’m going to write a novel here, short chapter by short chapter and I’m going to include the latest research and I’m going to imagine the entire story here for your delectation. If you want to start at the beginning, look left. Scroll down to LABELS. The first one is “A Fantastic Cancer Voyage”. Click on it. Scroll to the bottom and you will find episode on. Let me know what you think after you’ve read the whole thing!
 
Once the invitations and responses had come – word had gotten around about what she was doing – far more quickly than she’d expected, Dr. Olubunmi Nwagbara simply gone home.
 
Ohloo, as she insisted her friends call her, took the late maglev out of Rochester and the deep orbital well that was the Mayo Clinic, escaping thirty kilometers east to the small town of St. Charles. From there, she took her usual electric rental Mini Cooper north to the edge of Whitewater State Park in Elba Township. She owned a forty hectare organic produce hobby farm. She worked it during rare vacations and some weekends, but hired a tiny staff of three to tend to everyday operations, upkeep, housekeep, laundry, and meals. The two men were older, experienced and had been born in Nigeria in a village that spoke the same language she’d been born into – Efik. Her house help had shown up abused and nearly incoherent in the ER one night when Ohloo had been doing her residency.
 
During the Unsettled Twenties, social services had been overwhelmed and helpless, unable to give Diandra Kolchak a place to live. Ohloo had opened her apartment temporarily – and their friendship had been born.
 
Pulling up in the Cooper as it left the intense darkness surrounding the farm, she drove the curving asphalt. That hadn’t been her idea. The previous owner had done it. At least she’d had the concrete lions at the foot of the drive removed. She stopped on the cobbled courtyard.
 
Peter Usoro met her and took over. “Thank you, Sir,” she said. He smiled faintly, amused that she called him by the honorific. But that was how she had been raised. She went in. Di met her, took her coat and said, “There’s supper in the kitchen.”
 
“Thanks,” Ohloo said, lowering the imaginary personal shield she raised whenever she went into work. She sat on a stool and hooked her foot around a leg. “Local news,” she said. The small kitchen computer screen came to life, scrolling grain and pork futures, talking about seed and field treatments for the coming spring as well as announcing the latest bumper crop or famine.
 
After a while she realized that she was being watched. She turned and Di dipped a bit and said, “There’s someone here who’s been waiting to see you all day, Doctor.”
 
Scowling, she said, “They have the proper clearances?”
 
Di looked offended, returning the dark scowl. She stood with her hands hovering around her waist. She’d been trained in self-defense and body-guarding. She knew what she was doing and handled the household security quite well. Ohloo said, “Sorry, Di. Who is it?”
 
She knew the voice that spoke from the hallway leading to the guest suite and grinned as she turned.
 
The Prime Minister of Nigeria stepped into the kitchen light as Ohloo said, “Ediye!”
He opened his arms and she stepped into them as he said, “Daughter. I’ve missed you.” She hugged him and then he pushed her gently back, holding her at arm’s length. “You’ve been busy.”
 
She laughed, “So what else is new? I’ve been busy since before I was born.” Her mirth faded by a look in his eyes. She said, “What’s wrong?”
 
He shrugged, “Nothing that we can’t talk about later. I’m hungry.”
 
She stiffened. The least favorite of his many words from his mouth still had the power to make her feel both angry and ashamed. She called over her shoulder, “Diandra!”
 
His brows rose as he said, “Did your mother not teach you to cook?”
 
She pursed her lips and said, “As a matter of fact, no, Father. Mother did not teach me to cook. Cook did.”
 
“I don’t remember that...”
 
Ohloo clamped her jaw shut. She would not get into an argument. Instead she said, “We’re about to undertake a mission that might change the way Humanity looks at its world!”
 
His eyes darkened and he said, “That is the very reason I’ve flown here. To get you to stop.”

Image: http://medgadget.com/wp-content/uploads/2006/11/Fantastic-Voyage-200x290.jpg

Saturday, November 23, 2013

The Reconstruction Era – Part 8

From the first moment my wife discovered she had breast cancer, there was a deafening silence from the men I know. Even ones whose wives, mothers or girlfriends had breast cancer seemed to have received a gag order from some Central Cancer Command and did little more than mumble about the experience. Not one to shut up for any known reason, I started this blog…

“It appears that the next event is breast reconstruction!”

It’s strange because there’s not much to add here...

After the last surgery, life has been calm: we’re managing lymphedema (my wife does the sleeve, wrapping, and watching carefully in order to NOT injure the arm or hand – I do nightly massage to move fluid away from the arm and back and push it into the groin-area lymph nodes to be recirculated); she is taking care of the skin over the new implants; she is contemplating the final stages of reconstruction which are cosmetic – adding a “nipple” to each boob and getting an aureole tattooed on each.

As to that tattooing – the initial mention of it set me off into a spate of giggles. Not intentionally, mind you, but as my daughter has a tattoo on her arm and when she was younger, she asked if I’d accompany her to a certified tattoo parlor in an upscale neighborhood of the city we live in (where I felt like a forklift driver in a Williams-Sonoma Store) – I naturally thought of her and my daughter going into this establishment and inquiring after an aureole tattoo...

So, I’d best check the REALITY of this out. Here. Where I can apologize in public for my ridiculous vision.

Once the surgery to place the implants heals, there are two possible final steps. The site below has this to say, “Chances are, you have probably spent the last few months getting used to nipple-less or ‘Barbie’ breasts.” (Note: I was glad to see that I’m not the only one approaching this with a teeny bit of humor…)

The first choice here is of course, even whether to have the reconstruction of the nipple done at all. There’s no NEED to do it, but “For many women, this is the final step after a long journey.”

The second choice involves no surgery at all, but simply tattooing a realistic APPEARING nipple in place of a skin “tuck”. Tattoo artists are very proud of their work and finding an artist typically begins with your hospital. However, there are individuals who work out of their normal tattoo studios (http://vinniemyers.com/section/105672_Nipple_Areola_Tattooing.html) as well as working through hospitals and clinics.

The third choice is to have a surgeon make a pair of cuts into the skin surrounding the central spot then stitch them together. Once the cuts heal, the end result is a mound of living tissue, what is referred to as a “nipple mound”. Other methods are discussed below including skin grafts and a fat (or dermis) transplant or using the same substance used to create the implant supports to create a natural-looking nipple.

If the second or third choice is taken, an aureole can be created either from other skin grafts or using a tattoo artist to create the effect of the darker skin around the nipple.

This is the next step in the process and I’ll let you know the effects of the final decision!

Image: http://www.breastreconstructionprocess.com/myImages/nippleAreola.jpg

Monday, November 18, 2013

Round Three: Random Thoughts On Breast Cancer, Reconstructive Surgery, Lymphedema, Pain, Work, Suffering, and Joy

Two years ago – three this March 2014 – I would not have been able to imagine that anything could have possibly diverted my mind from thoughts of the breast cancer in my wife. Yet the diagnosis is past, the surgery is past, the chemotherapy is past, the hair growth is past, the reconstruction is mostly past…and now there are DAYS I don’t think about breast cancer.

Of course, cancer itself if never far away. The child of a colleague of mine was recently diagnosed with leukemia…and now from afar, I can see the horror and terror of the impending campaign against cancer all over again.

Yet, I have found progress and some amount of joy recently. Talking to an old friend of mine, we were catching up on the recent experiences of our wives, both of whom were diagnosed with breast cancer – my wife’s journey I’ve written  about here. He is a more private man and aside from telling his group of online friends about the diagnosis and some of the steps of the treatment, he really didn’t say much.

Until my wife was diagnosed as well. That commonality of dismay drew us together after years and while I don’t often see him, I feel a deep and abiding connection with him and know that our lives intertwined in a startling and unexpected way.

So I discovered that other things can now distract me. I’ve grown roots that I’d never needed before, and discovered a new strength I never knew I had. That I never knew was possible – it was a forged kind of strength. You know the kind if you’ve seen the LORD OF THE RINGS movies. It was the kind of strength that came from the reforging of something that was broken – Narsil – and then remade into a stronger, sleeker, more powerful weapon, the new sword, Andúril.

It accomplished great things once, that is, it stopped the dark lord, Sauron and nearly destroyed him. It was remade to accomplish greater things still and when Sauron once again attempted to take over Middle Earth, Andúril not only assured his defeat, it ushered in a New Age.

It appears to me that the New Age has not arrived. The health of my parents is deteriorating and my son left for 5 years of service in the Army.

It appears that while I may have been reforged in the fires of my wife’s struggle through breast cancer, I will be tempered by new fires – and perhaps pass through to be part of greater things.

Just in case you were wondering – this is called ramblings for a reason…


Sunday, November 17, 2013

Saturday, November 9, 2013

BREAST CANCER RESEARCH RIGHT NOW! 15 – A REAL Fantastic Cancer Voyage

From the first moment my wife discovered she had breast cancer, there was a deafening silence from the men I know. Even ones whose wives, mothers or girlfriends had breast cancer seemed to have received a gag order from some Central Cancer Command and did little more than mumble about the experience. Not one to shut up for any known reason, I started this blog…

Every month, I’ll be highlighting breast cancer research that is going on RIGHT NOW! Harvested from different websites, journals and podcasts, I’ll translate them into understandable English and share them with you. Today: http://www.medicalnewstoday.com/releases/268267.php

Nanotechnology is all about making things that are less that 100 nanometers [a nanometer is 1/1,000,000,000 (one BILLIONTH) of a meter!] in size.  That is pretty small, we are talking about atomic sized stuff.”

That’s like…STAR TREK stuff, right? “Beam me up, Scotty!” That kind of stuff?

Well now that you mention it, we DO live in the second decade of the 21st Century. Amazing things are happening. Why not being able to design atom-sized molecules to fight breast cancer!

Why bother – won’t chemo take care of most of the metastatic cells? The answer is “yes, but”. Not nice to hear, but true.

“‘When a patient is diagnosed with cancer, he or she undergoes surgery to remove the primary tumor, then undergoes chemotherapy to kill any residual disease, including distant micro-metastases,’ [Dr.  Efstathios] Karathanasis said...‘Chemotherapy drugs are very potent, but because they are randomly dispersed throughout the body in traditional chemotherapy, they aren't effective with the aggressive forms of cancer,’ he continued. ‘You have to give the patient so much of the drug that it would kill the patient before killing those micro-metastases...But delivering the killer drug only to micro-metastases is a challenge. They are hidden among healthy cells in such small numbers they don't make a blip on today's imaging screens.’”

While this project is ONLY IN THE FIRST STAGES OF ANIMAL TESTING, it holds a huge amount of promise. If the hope that has been placed in this therapy actually pans out, it would mean that lost hair, weakened immune systems, damage to the heart muscle and other debilitating side-effects would vanish and the chemo drugs would not only be more effective, they would also be cheaper.

Perhaps you’ve been reading my “novel-in-progress”, FANTASTIC CANCER VOYAGE. In it, I’ve postulated something that resembles this nanotech attack on cancer.

Based on the article, this is what would happen: nanotechs would create chains of atoms that would be attracted to the surface of cancer cells. Becoming cancerous changes the surface. Cells stop communicating with each other and don’t “know” when to stop growing, so the chains are attracted to these differences. The chains would link to the cancer cell and attached to the chain would be a ball of chemical. Once attached to a cancer cell, the ball would shatter at an electrical signal and deliver the chemical directly to the cancer cell – ONLY killing that cell.

This is further in the future than today – but it’s out there. And it’s coming. And it might just be a treatment for our daughters, our granddaughters…and certainly for our great-granddaughters!


Saturday, November 2, 2013

Metastatic Breast Cancer: Skin Cancer (aka Melanoma)

From the first moment my wife discovered she had breast cancer, there was a deafening silence from the men I know. Even ones whose wives, mothers or girlfriends had breast cancer seemed to have received a gag order from some Central Cancer Command and did little more than mumble about the experience. Not one to shut up for any known reason, I started this blog…

“Where’d this come from?”

Well, see, my brother, sister, and sister-in-law were all diagnosed with skin cancer and successfully treated. As well, an old friend and teaching colleague of mine was recently diagnosed and treated for skin cancer. (The worst part there was that he’d posted a picture of the excision on FaceBook and many (if not all) of US teased him about bonking his head, etc. Thoroughly stung when he later announced that it was a cancerous spot removed, I apologized both on his timeline and to him in person. NOT that I “should have known”, even so...)

Lately, I’ve had these dry, red patches on my face and while using lotion makes them fade, I have (duh) been wondering if they were signs of skin cancer. That led – at least in my mind – to wondering if there was any connection between breast cancer and skin cancer.

Not surprisingly, there is: “Since breast cancer is the most frequently diagnosed non-cutaneous (non-skin) cancer among women in the United States, it is not surprising that many individuals with breast cancer will develop melanoma (the deadliest form of skin cancer) and vice versa...recent studies exploring how often individual patients develop both cancers suggest that it [is] more than just coincidence: A recent study by Murphy, et al, for example, found that patients with either breast cancer or melanoma were almost four times more likely to develop the other malignancy than probability would lead researchers to expect. Specific causes linking the diseases may be in play, and genetic or environmental factors may also contribute. On the other hand, the association may at least partly result from more rigorous detection – in other words, a detection bias. This occurs when health care providers who carefully monitor cancer patients detect a second cancer that might otherwise have been missed.”

Also: “Sometimes cancer cells can start growing in the skin. This is not the same as having skin cancer, melanoma, or cutaneous T cell lymphoma (a type of lymphoma that affects the skin). The secondary cancer may start to grow on or near an operation scar where the primary cancer was removed. Or sometimes secondary skin cancers can grow in other parts of the body.

A secondary skin cancer looks like a pink or red raised lump (a bit like a boil). Skin nodules can be treated. It is important to tell your doctor if you think you have one, because if it is not treated, it may become ulcerated [has a ‘cauliflower’ look to it; also it can be weeping].”

So it appears that breast cancer CAN spread to the skin – yet it doesn’t seem to be a common occurrence. I had a bit of trouble even finding places where the two kinds of cancers were linked. That doesn’t make it comforting – just one less-likely thing to worry about.