Saturday, May 26, 2018

ENCORE #88! – A Vaccine Against Breast Cancer!?!?!?!?!?!?!


From the first moment my wife discovered she had breast cancer, there was a deafening silence from the men I know. Even ones whose wives, mothers or girlfriends had breast cancer seemed to have received a gag order from some Central Cancer Command and did little more than mumble about the experience. Not one to shut up for any known reason, I started this blog…That was four years ago – as time passed, people searching for answers stumbled across my blog and checked out what I had to say. The following entry appeared in April of 2015.

NOTE THE UPDATE ON LAST SATURDAY'S POST BELOW!

NOT TODAY OR TOMORROW!!!!!

But maybe someday in the not-too-distant-future!

One of the things that sometimes bugs me about science fiction that’s supposed to be set in the distant future, is when they pull a stunt with the sole intent of making the “futuristic story” relevant to today. I’m reading a novel right now in which soldiers swear with the “f-word”. I can’t help think, “Oh, come on! You don’t REALLY think cuss words are going to stay exactly the same and have the same shock value five hundred or a thousand years in the future, do you?”

Another one, this time relevant to breast cancer, is when the President of the Twelve Colonies on the re-imagined BATTLESTAR GALACTICA is diagnosed with breast cancer. “At her doctor's appointment, Roslin is told that she has breast cancer and a year to live.”

Far be it from me to second-guess a writer and argue for dramatic impact, but this society has TWELVE separate worlds it governs; it has the capability to build (from scratch) TWELVE massive, monstrous, huge star ships capable of traveling at trans-light speeds – but not a single person ever thought to apply technology to breast cancer research?

Thanks be to God we live in this society! While the BC vaccine is by no means “just around the corner”, there is excellent evidence from a few small studies that it may be something that young adults may experience as a matter of course. There’s a glimmer of hope of creating a vaccine against breast cancer!

Something called “Mammaglobin-A (MAM-A) is overexpressed in 40% to 80% of primary breast cancers.” Because it is so common in breast cancers, researchers can use it as a marker – like a blinking light on top of a water tower! – and design T-cells (also known as white blood cells – the kind that fight disease and infection in Humans) that will specifically attack and eat the cancer cells. “This makes MAM-A a great target for a new cancer therapy as it could hopefully be used for the vast majority of patients with early stage and metastatic disease, where the protein is also found to be overexpressed. The vaccine works by priming white blood cells to target and destroy other cells presenting MAM-A, and the vaccination study was the first of this type against this target.”


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