Saturday, March 5, 2016

BREAST CANCER RESEARCH RIGHT NOW! #43 : SHARKS DON’T GET CANCER!!! *Lie*


https://upload.wikimedia.org/wikipedia/commons/4/40/Naked_mole_rat.jpgFrom the first moment my wife discovered she had breast cancer, there was a deafening silence from the men I know. Even ones whose wives, mothers or girlfriends had breast cancer seemed to have received a gag order from some Central Cancer Command and did little more than mumble about the experience. Not one to shut up for any known reason, I started this blog…

Every month, I’ll be highlighting breast cancer research that is going on RIGHT NOW! Harvested from different websites, journals and podcasts, I’ll translate them into understandable English and share them with you. Today: http://www.scientificamerican.com/article/sharks-do-get-cancer-tumor-found-great-white/, http://qz.com/523764/these-two-cancer-resisting-animals-offer-hope-for-a-human-cure/

Cancer.

I hate that word.

Why can’t we just get the secret of sharks, because as everyone knows, sharks don’t get cancer!

Unfortunately, that’s a lie...following the link above will give you a look at a truly gross picture that proves, once and for all that sharks DO get cancer! So stop spreading the fable!

On the other hand, ARE there living things that don’t experience the uncontrolled growth of cells?

As far as we can tell, yes. They are NOT as horrifyingly threatening as the creature that bears razor-sharp teeth and was immortalized by a musical bar containing “a simple alternating pattern of two notes—variously identified as E and F or F and F sharp”. (https://en.wikipedia.org/wiki/Jaws_(soundtrack))

According to the second article, while elephants DO get cancer, the rate is remarkably less that Humans: “only 5% of elephants die of cancer in comparison to more than 20% humans”, this despite the fact that there are more cells in an elephant to GET cancer with!

The other animal that doesn’t get cancer is the…(pause for effect) naked mole rat.

Ewwww…

However, “as far as we know, [these animals] never develop cancer. Even if researchers try to induce cancer through artificial means.” The reason appears to be that there’s a substance called hyaluronan between rat cells. It’s a polymer, a long string of natural sugars that both makes the cells stronger as well as prevents the wild overgrowing of cells that we call cancer.

The thing is, is that Humans DO have hyaluronan, but it’s used for different things like balancing the exchange of water and plasma in the bloodstream, it may be a factor in cell division (aka mitosis), and cell movement. It also seems to play a role in deciding what kind of cell will grow from a basic type – muscle, nerve, liver, etc. It’s recognized as having the ability to protect cells and as such, it is used in eye surgery. Even so, it ALSO appears that conversely to what it does in the naked mole rat, hyaluronan that accumulates in between cells can cause them to malfunction.

Complex reactions that we don’t quite understand yet – but…but…but… “Rochelle Buffenstein, a physiologist at the University of Texas Health Science Center [said], ‘As we learn more about these cancer-resistant mechanisms that are effective and can be directly pertinent to humans, we may find new cancer prevention strategies.’”


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