Saturday, July 23, 2016

BREAST CANCER RESEARCH RIGHT NOW! #47: Fasting and Chemotherapy Together May be MORE Effective Than Chemo ALONE!

From the first moment my wife discovered she had breast cancer, there was a deafening silence from the men I know. Even ones whose wives, mothers or girlfriends had breast cancer seemed to have received a gag order from some Central Cancer Command and did little more than mumble about the experience. Not one to shut up for any known reason, I started this blog…

Every month, I’ll be highlighting breast cancer research that is going on RIGHT NOW! Harvested from different websites, journals and podcasts, I’ll translate them into understandable English and share them with you. Today: https://www.sciencedaily.com/releases/2016/07/160711150926.htm

The idea that chemotherapy and fasting together enhance the “power” of the chemo has been around for some time:

“Gene expression assays and molecular analyses suggested that, in cancer cells but not healthy cells, fasting and chemo together induce a 20-fold increase in DNA damage, an increase in oxidative stress, and higher incidence of cleaved caspase 3, a protein that induces cell death.

“Longo hypothesizes that, while normal cells are well-equipped to deal with starvation by slowing their metabolism to just essential activities, cancer cells ‘became better at growing and growing and worse at adapting to new conditions.’ When cancerous cells are faced with a hostile environment, such as starvation, they become weak and shut down. ‘And, when they become weak, chemotherapy has an easier time,” he added. However, he emphasized, this is still a hypothesis.’” (2012)

There has been clear evidence of the positive effects of fasting during chemotherapy at least since 2009 (see second link below). Though we never heard a peep about this when my wife was undergoing chemo, it makes perfectly good sense.

In fact, fasting for health and spiritual development has an extremely long and documented history. In the Old Testament of the Bible, it appears as early as the book of Exodus, and specific to an individual in Second Samuel. A commentary on fasting notes, “…the OT uses fasting and abstinence from food to point to something even more necessary for life—communion with and dependence on God.”

Outside of religion: “Herbert Shelton…wrote ‘Fasting must be recognized as a fundamental and radical process that is older than any other mode of caring for the sick organism, for it is employed on the plane of instinct...’”

So, where was fasting when my wife went through chemo? The same place as everything else: in the literature but applied entirely according to the whims and knowledge of the doctor.

So, where is fasting today? It’s finally entered the realm of SPECIFICS: “Fasting is known to increase positive outcomes during cancer treatment, and now two independent studies in mice show that fasting, either through diet or drugs, during chemotherapy helps increase the presence of cancer-killing T cells.”

While the study doesn’t prove it, the lead doctor speculates: “…fasting, which would have been very common for our ancestors, was a tool to reboot the immune system and prevent the circulation of cancer cells. ‘This coordinated multifaceted effect seems too good to be true," he says. "It may not be a coincidence, but a very precisely evolved process that is meant to get rid of bad cells.’”

While I hesitate to draw any conclusions this early in the appearance of the research, I might also speculate that as Westerners, we have made an art of satisfying every whim and fancy, from having a never-ending supply of food available to us either to go get or, increasingly, to have delivered to us with no more effort on our part than the exercise of our finger muscles to pretty much having anything else we want. Obesity is now public enemy number one and it is obvious that one of the causes is our constant eating. Whether we were created to fast or evolved to fast, is it any surprise that cancers are eating us up? Denying ourselves MAY just be a survival imperative, and if you link to and read this article, you might also notice that doctors are QUICKLY finding ways around the actual “denial of whims” by creating something they call, “caloric restriction mimetics--drugs that selectively trigger some of the biochemical cascades that result from starvation but without the weight loss--”. All of this so we can trick our bodies into thinking they’re fasting while we continue to eat whatever and whenever we want.

What if doctors actually promoted, you know, fasting? I would add a snarky comment here, but I won’t. You can imagine it yourselves.


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