Saturday, November 5, 2016

BREAST CANCER RESEARCH RIGHT NOW! #50: Breast Cancer and Prostate Cancer In Relatives May Indicate an Increased Chance of Breast Cancer

From the moment my wife discovered she had breast cancer, there was a deafening silence from the men I know. Even ones whose wives, mothers or girlfriends had breast cancer seemed to have received a gag order from some Central Cancer Command and did little more than mumble about the experience. Not one to shut up for any known reason, I started this blog…

Every month, I’ll be highlighting breast cancer research that is going on RIGHT NOW! Harvested from different websites, journals and podcasts, I’ll translate them into understandable English and share them with you. Today: http://www.breastcancer.org/research-news/prostate-cancer-related-to-bc-risk

So…my wife had breast cancer. My dad had prostate cancer – but my MOM didn’t have breast cancer and I don’t have prostate cancer…

So, what does this mean for my kids?

Backtrack for a second: I have a BS in biology with additional classes in earth, space, soil, and chemical sciences that allow me to teach (at least one class of) anything from astronomy to zoology. I pretty much know what I’m talking about when it comes to genetics, cancer, and Alzheimer’s. NOT because the degree magically imparted on my special knowledge, but because I can read the reports, papers, abstracts, and scholarly articles and then understand them (sometimes with a bit of research).

So – I made a map, or a Cancer Family Tree. You can see it above.

Based on this article and my Cancer Family Tree, I can say that my daughter is NOT in this class of possible breast cancer risks. My sister isn’t, either.

I can’t say that I’m breathing a sigh of relief because we ALL know that BC is far more complicated than this. But it’s somewhat reassuring.

“‘These findings are important in that they can be used to support an approach by clinicians to collect a complete family history of all cancers -- particularly among first-degree relatives -- in order to assess patient risk for developing cancer,’ said Jennifer Beebe-Dimmer, Ph.D., M.P.H. of the Barbara Ann Karmanos Cancer Institute and Wayne State University, who was the lead researcher. ‘Families with clustering of different tumors may be particularly important to study in order to discover new genetic mutations to explain this clustering.’”

I suppose I’ve “known” this all along, but seeing it in such stark terms, I can see that my family has a long history of cancers…not just one kind: lung, skin, prostate. My wife’s family is just as varied: lung, liver, breast cancers. It looks like my kids have an entire suite of things to keep an eye on. Not to worry. Strides are being made in cancer research all the time. It’s why we host such events as Relay For Life, Susan B. Kommen events, and all the others.

A cautionary note. Any of you ever see I AM LEGEND? “. The story is set in New York City after a virus, which was originally created to cure cancer, has wiped out most of mankind, leaving Neville as the last human in New York...” in a city infested with zombie-like nocturnal things. The movie opens with “Emma Thompson has an uncredited role as Dr. Alice Krippin, who appears on television explaining her vaccine for cancer that mutated into the ‘zombie’ virus.”

The cautionary note? Cancer is complex, varied, and has dozens of factors that affect it. There IS no straight line between genetics, environment, lifestyle and the onset of cancer in Humans. A Human-engineered vaccine against cancer could very easily succumb to natural forces and turn into something terrifying.

On THAT happy thought, see you later!


Image: Personal camera, © Guy Stewart 2016

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