Saturday, November 26, 2016

ENCORE #50! – Does EVERYONE, ALWAYS Need Radiation After A Lumpectomy?

From the first moment my wife discovered she had breast cancer, there was a deafening silence from the men I know. Even ones whose wives, mothers or girlfriends had breast cancer seemed to have received a gag order from some Central Cancer Command and did little more than mumble about the experience. Not one to shut up for any known reason, I started this blog…That was four years ago – as time passed, people searching for answers stumbled across my blog and checked out what I had to say. The following entry appeared in August 2013. The root of this one is from: http://www.medicalnewstoday.com/releases/264999.php

One of the most AMAZING things about consistently looking at current breast cancer research is that the discoveries seem to be never-ending. I can’t imagine ever stumbling across a headline that reads, “Scientists Know Everything About Breast Cancer, Research Centers Closed”…

Aside from the shock to breast cancer researchers if they actually reached their ultimate goal, I wonder what the next frontier would be? Certainly the world of research changed when smallpox was finally vanquished or we conquered polio.

At any rate, there’s news now that breast cancer treatment may be taking another turn – women who contemplate a lumpectomy typically follow up with both radiation and some sort of chemotherapy.

One research team is now proposing that treatment centers and doctors WEIGH the advantages and disadvantages of subjecting a woman to sometimes debilitating treatment with radiation. “The most contentious issue surrounds radiotherapy and whether all patients undergoing breast-conserving surgery should receive it. The authors believe that if toxic effects of radiotherapy exceed any oncological gains amongst DCIS patients, it is likely to lead to a higher all-cause mortality rate.”

In other words, it’s a case of “if they don’t need it, don’t do it” school of medicine.

While the research DOES NOT SAY RADIATION TREATMENT IS A WASTE OF TIME OR HARMFUL IN ALL WOMEN, they do note that “Present treatment options for DCIS [ductal in situ carcinoma – the most common form of breast cancer] are acknowledged as being excessive for many patients, and the aim of molecular profiling is to ensure that additional treatments such as radiotherapy are restricted to patients at highest risk of invasive recurrence."

What is molecular profiling? “Molecular profiling [looks at] the [patient’s] genetics and... [looks for] molecules found in the blood, other body fluids or tissues. Based on the information gathered from a patient’s tumor, doctors are able to identify the appropriate therapies that target[s that] patient’s cancer cells.”

So, doctors are working to first detect breast cancer as early as possible, then treat the cancer effectively using ONLY what is needed to heal the patient. This would include the recent push to only remove SENTINEL lymph nodes that test positive for cancer rather than entire lymph node structures along with recent research that indicates that it MAY be possible to reattach the lymph ducts from a limb back into the blood stream if a large number of nodes were removed, thereby reducing the incidence of lymphedema...but that’s the subject of another post!

Targeted treatment for maximum impact with minimal damage? Sounds like a good plan to me.


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